Andersen has been one of the leagues breakout stars this season, despite initially struggling to adapt to life in Italy. Plenty of top European sides have been linked with a move for the Dane, one of which is Tottenham, who appear close to finalising a deal for Andersen.
News of Tottenhams agreement comes from Tuttosport (via Sport Witness), who state that Sampdoria official Antonio Romei flew to London on Tuesday to discuss a deal for the €25m-rated defender.
However, according to Calciomercato, AC Milan have now joined the race for Andersens signature, and could seek to open negotiations as soon as possible in an attempt to halt Tottenhams progress.
Milan want somebody to partner 24-year-old Alessio Romagnoli in the heart of their defence, and they see Andersen as the ideal candidate, as the two could line up alongside each other for the foreseeable future.
Inter are also said to be serious contenders for Andersens signature, whilst the likes of United, Juventus and Paris Saint-Germain are thought to be plotting a summer move for the 22-year-old.
Andersen has made 28 appearances for Sampdoria this season, establishing himself as one of the sides most important players. The Blucerchiati currently sit ninth in the Serie A table, and many credit this position to the towering Danes emergence as a future star.
Tottenham have long been keen on Andersen as they seek to bolster their defence for the foreseeable future. Both 30-year-old Toby Alderweireld and 31-year-old Jan Vertonghen have just 18 months remaining on their contracts at the club, and Mauricio Pochettino appears to be preparing for the future.
Alderweireld has been the subject of serious interest from the likes of United, Chelsea and Barcelona in the past, and now has a £26m release clause in his contract which became active after Tottenham automatically extended the Belgians deal in December. As a result, they could be powerless to prevent his exit, which could prompt a summer deal for Andersen.